Lipoma is the most common benign mesenchymal tumor of soft tissues in humans. It occurs mainly in the trunk, in the extremities of the body and in the neck region, but only 0.1 to 5% are in the oral region. Clinically, the lesion located in the oral cavity is well-defined, asymptomatic, and the color varies according to its distribution in the oral tissues. They may be sessile or pediculated, with a smooth surface, gelatinous appearance, and may vary in size. The treatment commonly indicated consists of total excision of the lesion, which is an essential factor for the success of the treatment. The objective of this study is to report and discuss a case of lipoma located in the oral space, treated surgically with intraoral access under local anesthesia and in an outpatient setting.